| Autor: |
Rogausch, H., Kaffarnik, H., Schubotz, R., Mühlfellner, G., Schneider, J. |
| Zdroj: |
Biorheology; October 1978, Vol. 15 Issue: 3-4 p303-310, 8p |
| Abstrakt: |
Lysolecithin induces a disc-echinocyte transformation at the moment of contact with normal red cells. This is accompanied by a transient increase in the viscosity of red-cell suspensions, which returns spontaneously to normal during prolonged contact with lysolecithin. Since metabolic processes of the red cell are involved in the normalization of viscosity, the term “red-cell adaptation” is used for this property. The present paper shows that red-cell adaptation to lysolecithin is absent in hyperlipemic patients. In addition, 25% of the latter had less deformable red cells in freshly drawn venous blood samples. Interpretation of the mechanisms involved in red-cell adaptation and its failure leads to the assumption that there may be a link between reversible (by lysolecithin) and irreversible (in venous blood) reductions of red-cell deformability. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
