Hereditary Hemorrhagic Telangiectasia

Autor: Kühnel, Thomas, Wirsching, K., Wohlgemuth, W., Chavan, A., Vielsmeier, V.
Zdroj: Otolaryngologic Clinics of North America; 20240101, Issue: Preprints
Abstrakt: Hereditary hemorrhagic telangiectasia (HHT) describes the presenting manifestations of a disorder that is characterized by dilated blood vessels. HHT is inherited as an autosomal dominant trait with variable penetrance. The abnormal vascular structures (dysplasias) can affect all the organs in the human body. The link between a physical stimulus and new lesion development has been established for mucosal trauma owing to nasal airflow turbulence, for ultraviolet exposure to the fingers, and for mechanical trauma to the dominant hand. The pressing question then is whether HHT treatment constitutes a stimulus that is sufficient to trigger new lesion development.
Databáze: Supplemental Index