Collagenase Clostridium histolyticumin the Treatment of Peyronie's Disease—A Review of the Literature and a New Modified Protocol

Autor: Abdel Raheem, Amr, Johnson, Mark, Abdel-Raheem, Tarek, Capece, Marco, Ralph, David
Zdroj: Sexual Medicine Reviews; October 2017, Vol. 5 Issue: 4 p529-535, 7p
Abstrakt: Peyronie's disease (PD) is a common condition that results in penile deformity, which makes sexual intercourse difficult or impossible, and causes psychological, emotional, and relationship difficulties for the man affected and his partner. Collagenase Clostridium histolyticum(CCH; Xiapex, Xiaflex) is the first licensed non-surgical treatment option for PD. The safety and efficacy have been demonstrated in two large phase III randomized controlled trials (IMPRESS I and IMPRESS II).
Databáze: Supplemental Index