| Autor: |
Schmidt, Joseph D., Feldbush, Thomas L., Weinstein, Stephen H., Bonney, William W. |
| Zdroj: |
The Journal of Urology; March 1976, Vol. 115 Issue: 3 p293-295, 3p |
| Abstrakt: |
Serum concentrations of Immunoglobulins G, A and M (IgG, IgA and IgM) were measured by immunodiffusion In a control population of 58 patients and In 165 patients with cancer of the pros-state, bladder, kidney or testis. Tumor patients were ranked according to clinical staging. In a smaller group of patients serum levels of IgE were measured by radioimmunoassay. IgG, IgA and IgM concentrations did not correlate with staging or the presence of malignancy. However, a statistically significant correlation between increased IgE levels and advanced bladder cancer (stages D1and D2) stimulated us to study more patients with bladder tumors. In a subsequentgroup of 22 bladder tumor patients this trend could not be reproduced. IgE levels did not correlate with a history of allergy in any of the patients tested. Concentrations of immunoglobulins G, A, M and E seem to be unchanged in genitourinary malignancies, although their functional role here has not been assessed qualitatively. |
| Databáze: |
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| Externí odkaz: |
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