The Effect of Steroids on Theophylline Absorption

Autor: Tatsis, G., Orphanidou, D., Douratsos, D., Mellissinos, C., Pantelakis, D., Pipini, E., Jordanoglou, J.
Zdroj: Journal of International Medical Research; July 1991, Vol. 19 Issue: 4 p326-329, 4p
Abstrakt: The effect of hydrocortisone on plasma theophylline concentrations was evaluated in 20 patients suffering from chronic bronchitis or stable bronchial asthma. Choline theophyllinate (400 mg) was orally administered every 12 h for 8 days and blood samples were taken every 2 h during the day for the measurement of theophylline concentrations. Intravenous bolus injections of 500 or 1000 mg hydrocortisone on day 5 or day 7, respectively, did not significantly alter plasma theophylline concentrations.
Databáze: Supplemental Index