The Cell Surface Antigen A, B or O(h) as an Indicator of Malignant Potential in Stage a Bladder Carcinoma: Preliminary Report

Autor: Bergman, Stuart, Javadpour, Nasser
Zdroj: The Journal of Urology; January 1978, Vol. 119 Issue: 1 p49-51, 3p
Abstrakt: The presence or absence of cell surface antigens (A, B and H) on the cell surface of bladder tumors has been studied. The major blood group antigens A, B or O(H) are present on normal bladder epithelium but are not present on some low grade and low stage papillary transitional cell carcinomas of the bladder. We have demonstrated that of 5 stage A bladder tumors that have not recurred in at least 5 years 3 retained the cell surface antigens, while tumors that have recurred locally, invaded or metastasized had lost these cell surface antigens on the original stage A tumor.
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