| Autor: |
Weckworth, Paul F., Johnson, Hjalmar W., Pantzar, J. Tapio, Coleman, Gerald U., Masterson, John S.T., McGillivray, Barbara, Tze, Wuan J. |
| Zdroj: |
The Journal of Urology; January 1988, Vol. 139 Issue: 1 p91-94, 4p |
| Abstrakt: |
We report 4 cases of mixed gonadal dysgenesis with a karyotype containing a dicentric Y chromosome. All cases were mosaic with 45X and 46X, dic(Y) cell lines. Of the patients 1 had ambiguous genitalia and some features of Turner’s syndrome, 2 had classical features of Turner’s syndrome with normal female external genitalia and 1 had no features of Turner’s syndrome but he presented with penoscrotal hypospadias, inguinal hernia and cryptorchidism. Female gender assignment and early total gonadectomy should be considered when a dicentric Y chromosome is present in cases of mixed gonadal dysgenesis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
