| Autor: |
Schornagel, Jan H., Verweij, Jaap, Huinink, Wim W. Ten Bokkel, Klijn, Jan G.M., De Mulder, Pieter H.M., Debruyne, Frans M.J., van Deijk, Wijgert A., Roozendaal, Klaas, Kok, Tjebbe C., Veenhof, Kees H.N., Berkel, Johannes, van Oosterom, Allan T. |
| Zdroj: |
The Journal of Urology; August 1989, Vol. 142 Issue: 2 p253-256, 4p |
| Abstrakt: |
A total of 66 patients with advanced renal cell cancer received a combination of recombinant interferon alpha-2a (18 times 106units subcutaneously 3 times weekly) and vinblastine (0.1mg. per kg. intravenously every 3 weeks). Four patients were ineligible and 6 were inevaluable for response but evaluable for toxicity. There were no complete and 9 partial responses among the 56 evaluable patients, for a response rate of 16 per cent. Median duration of response was 26 weeks, with a range of 8 to 50 weeks. Responses were observed predominantly in patients with lung and soft tissue metastases. Patients who had undergone nephrectomy did not show a better response rate than those who had not. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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