| Autor: |
Prout, George R., Shipley, William U., Kaufman, Donald S., Heney, Niall M., Griffin, Pamela P., Althausen, Alex F., Bassil, Barbara, Nocks, Barry N., Parkhurst, Edward C., Young, Hugh H. |
| Zdroj: |
The Journal of Urology; November 1990, Vol. 144 Issue: 5 p1128-1134, 7p |
| Abstrakt: |
Preliminary data are presented of a clinically feasible pilot study to select a significant subgroup of patients among those with muscle-invading bladder tumors for local cure and bladder preservation, while also to offer all patients the possibility of preventing the development of distant metastases. Transurethral debulking surgical resection was combined with neoadjuvant methotrexate, cisplatin and vinblastine chemotherapy plus 2 additional courses of cisplatin and 4,000cGy. If tumor was found on cystoscopic re-evaluation by biopsy and for cytology after cisplatin and partial irradiation (4,000cGy.) immediate cystectomy was advised. If tumor was not found consolidation by a radiotherapy boost to a total of 6,480cGy. plus 1 additional course of cisplatin was given. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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