Immunomodulation in Horses

Autor: Rush, Bonnie R., Flaminio, M. Julia B.F.
Zdroj: Veterinary Clinics of North America: Equine Practice; April 2000, Vol. 16 Issue: 1 p183-197, 15p
Abstrakt: Nonspecific immunomodulators are substances that induce nonantigen–specific enhancement of the body’s native or acquired defense mechanisms. Immunomodulant preparations are most often used for treatment of chronic, viral, or bacterial infection with evidence of secondary immunosuppression. The proposed mechanism of action of these products is macrophage activation and subsequent release of cytokines that enhance humoral and cell-mediated immunity. In equine medicine, nonspecific immunostimulant products are used for prevention and treatment of infectious respiratory disease and treatment of sarcoid skin tumors.
Databáze: Supplemental Index