The Incidence and Antibiotic Susceptibility of Branhamella catarrhalisin Respiratory Infections

Autor: Colder, Margaret, Croughan, Michael, McLeod, Dwight, Ahmad, Fareed
Zdroj: Drugs; May 1986, Vol. 31 Issue: Supplement 3 p11-16, 6p
Abstrakt: The incidence ofBranhamella catarrhalis in respiratory infections at City Hospital, Edinburgh from January 1981 to April 1984 is described. Beginning in January 1982 there was an increased incidence associated with a high proportion of β-lactamase- producing strains. The number of these strains increased: from January 1981 to April 1983, 61% of strains produced β -lactamase, and 83% produced β -lactamase from January to April 1984. 53% of patients were infected in hospital. Environmental studies showed that 7% of staff and 8% of patients were carriers; there was also circumstantial evidence of ward and patient- to- patient infection. The antimicrobial susceptibility of 54 clinical strains was tested: all strains were resistant to trimethoprim but were susceptible to clavulanic acid plus amoxycillin, chloramphenicol, erythromycin, co- trimoxazole, cefotaxime and cefuroxime. β -Lactamase- negative strains were uniformly susceptible to penicillin and ampicillin.
Databáze: Supplemental Index