CXCR4 (CD184) expression on stem cell harvest and CD34+cells post-transplant

Autor: Asfour, Inas, Afify, Hanaa, Elkourashy, Shaza, Ayoub, Maryse, Kamal, Gihan, Gamal, Mary, Elgohary, Ghada
Zdroj: Hematology/Oncology and Stem Cell Therapy; June 2017, Vol. 10 Issue: 2 p63-69, 7p
Abstrakt: CXCR4 is a receptor for stromal-derived factor-1 (SDF-1), a molecule that has a chemotactic activity for lymphocytes and is important in homing of hematopoietic stem cells to their adult marrow. We evaluated the CXCR4 (CD184) expression in the harvest cells and in the post-transplant bone marrow (BM) and its relation to engraftment, as determined by the consensus criteria and chimerism.
Databáze: Supplemental Index