Alectinib for Patients with ALKRearrangement–Positive Non–Small Cell Lung Cancer and a Poor Performance Status (Lung Oncology Group in Kyushu 1401)

Autor: Iwama, Eiji, Goto, Yasushi, Murakami, Haruyasu, Harada, Taishi, Tsumura, Shinsuke, Sakashita, Hiroyuki, Mori, Yoshiaki, Nakagaki, Noriaki, Fujita, Yuka, Seike, Masahiro, Bessho, Akihiro, Ono, Manabu, Okazaki, Akihito, Akamatsu, Hiroaki, Morinaga, Ryotaro, Ushijima, Shinichiro, Shimose, Takayuki, Tokunaga, Shoji, Hamada, Akinobu, Yamamoto, Nobuyuki, Nakanishi, Yoichi, Sugio, Kenji, Okamoto, Isamu
Zdroj: Journal of Thoracic Oncology; July 2017, Vol. 12 Issue: 7 p1161-1166, 6p
Abstrakt: Alectinib has shown marked efficacy and safety in patients with anaplastic lymphoma receptor tyrosine kinase gene (ALK) rearrangement–positive NSCLC and a good performance status (PS). It has remained unclear whether alectinib might also be beneficial for such patients with a poor PS.
Databáze: Supplemental Index