Functional polymorphism rs1024611 in the MCP1gene is associated with the risk of varicose veins of lower extremities

Autor: Shadrina, Alexandra S., Smetanina, Mariya A., Sevost'ianova, Kseniya S., Seliverstov, Evgenii I., Ilyukhin, Evgeny A., Voronina, Elena N., Zolotukhin, Igor A., Filipenko, Maxim L.
Zdroj: Journal of Vascular Surgery: Venous and Lymphatic Disorders; July 2017, Vol. 5 Issue: 4 p561-566, 6p
Abstrakt: Monocyte chemoattractant protein 1 (MCP-1) is a chemokine responsible for monocyte, basophil, and T-lymphocyte attraction. Polymorphism rs1024611 located in the regulatory region of the MCP1gene has previously been shown to be associated with increased MCP-1 production. In our study, we aimed to examine the association of rs1024611 with the risk of primary varicose veins (PVVs) of lower extremities.
Databáze: Supplemental Index
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