| Autor: |
Mort, J S, Poole, A R, Decker, R S |
| Zdroj: |
Journal of Histochemistry and Cytochemistry; May 1981, Vol. 29 Issue: 5 p649-657, 9p |
| Abstrakt: |
The proteinase cathepsin B has been localized in human fibroblasts using a monospecific antiserum that reacts in a precipitating manner with the denatured enzyme only. The distribution of staining as revealed by both direct and indirect immunofluorescence indicates a typical lysosomal localization similar to that observed for cathepsin D. Using dual localization methods employing fluorescein- and tetramethylrhodamine-labeled affinity purified antibodies both proteinases were usually observed in the same lysosome, indicating a combined role in intracellular digestion. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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