| Autor: |
Koropouli, M, Avanidi, M, Valari, V, Papadimas, M, Fillipidis, M |
| Zdroj: |
Pediatric Research; August 2005, Vol. 58 Issue: 2 p390-390, 1p |
| Abstrakt: |
Neonatal sepsis continues to speculate neonatologists all over the world, while it remains the prime cause of mortality and morbility of neonates, and especialy the preterms.Aim: Was to enrole sepsis, the pathogenic microbes and their sensitivities and especially their characteristics as the time of their appearence (precocious or belated) and the place (nosocomial or not).Method: From 1/1/2003 to 28/2/2004 (14 months) we recorded the infections with positive blood cultures. Our material was 863 neonates who were hospitalised in our NICU.Results: 654 out of blood cultures that were sent, 35 were positive in 32 neonates. The frequency of sepsis was 6,21%. The mortality was 6% (2 neonates) 15/32 neonates were < 35 weeks. 12 neonates were infected by nosocomial infection and all of them were preterm. The pathogenetic organism was gram (-) bacteria (8/12). The most common microbe was gram (+) coccus (staphylococcus). 19 neonates were affected from kl. Pneumoniae. All gram (+) were sensitive to Vancomycin and all gram (-) to Imipenem, Amicasin and Ciprofloxacin. 15/32 neonates had the infection in the first 72 hrs of life and all were gram (+) except one. 12/15 were full term neonates. Premature rupture of membranes had only two neonates. There was not found any relationship between: sepsis and diabetes mellitus of the mother, multiple pregnancies, meconium aspiration, sex, and way of delivery.Discusion and Conclusion: The resistant to oxacyclin staphylococcus aureus and epidermdis as well as the multiresistant gram (-) bacteria, are the most frequent bacteria of sepsis in our unit. The nosocomial infections are usually caused by klebsiella (ESBL). The early onset sepsis is caused almost exclusively by Gram (+) microbes and have to do with full term neonates. |
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