Autor: |
Anagnostakou, M, Peristeri, J, Spanos, Th, Christodoulou, M, Lipsou, N, Xanthou, M |
Zdroj: |
Pediatric Research; July 1994, Vol. 36 Issue: 1 p66A-66A, 1p |
Abstrakt: |
The aim of our study was to measure the concentrations of Fibronectin in LBW neonates during infections, as well as the correlation of blood levels with immunoglobulin administration. Fibronectin (FN) levels were measured from the serum of 16 premature neonates BW=1150±260gr and GA= 29±2w. Samples were taken weekly from the 30th week of gestational age until the 38th using the method of tholosimetrias. During this period the neonates presented with 1 or 2 episodes of sepsis proved by clinical and laboratory investigation. Before or during infection, the neonates along with antibiotics, received sandoglobulin in total dose 2.5g IV. Our results show a strong increase of FN levels between 30-34w ga p<0.007, but we did not find a significant increase between 34-38w p<0.230 in healthy babies. Taking into consideration the babies with infection our results indicate that there was a severe drop in Fibronectin levels. The babies who received Sandoglobulin had a less severe drop in Fibronectin levels than those who did not receive it (p<0.038). |
Databáze: |
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