| Autor: |
Brudno, D Spencer, Parker, Donald H, Burch, Kenneth D, Steinhart, Curt M |
| Zdroj: |
Pediatric Research; April 1987, Vol. 21 Issue: 4 p198A-198A, 1p |
| Abstrakt: |
This study was performed to evaluate improved software that non-invasively measures Effective Pulmonary Blood Flew (QEP), Lung Tissue Water (Vt), Lung Diffusion for carbon monoxide (DLoo), and Functional Residual Capacity (FRC).A modified non-invasive method for the measurement of four cardiopulmonary parameters (CPP) which can be measured only with an accepted gas rebreathing method or by invasive means was developed to improve speed of data acquisition and analysis, and ease of use. The rebreathing system includes a Perkin Elmer Respiratory Gas Analyzer MGA-1100, an IBM-XT computer and a valving device. Nine dogs were instrumented to invasively measure thermodilution cardiac output and measure mixed venous and systemic oxygen saturations. Measurements of CPP were made before and after invasive measurements and averaged.Rebreathing QEP correlated well with the invasive QEP (p<0.0001). Vt, DLco and FRC decreased during lung injury (p<0.00001 for all three). FRC increased proportional to increased PEEP from 0 to 15 on H2O (p<0.005).Computation time from the end of a 25 second sampling time to acquisition of results was less than 2 minutes. One program is utilized during the sampling, computation, disk I/O and printing modules. Raw gas concentration vs. time, and log gas concentration vs. time curves are displayed for selection of the window used for calculation of CPP. This study demonstrates a powerful software package for the non-invasive measurement of CPP. |
| Databáze: |
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