| Autor: |
Mayfield, Steven, Stonestreet, Barbara S, Brubakk, Ann Marie, Shaul, Philip W, Oh, William |
| Zdroj: |
Pediatric Research; April 1985, Vol. 19 Issue: 4 p353A-353A, 1p |
| Abstrakt: |
We studied regional Q and its regulation during ECS in seven 3-4 day old piglets by measuring cardiac output(CO), organ Q, arterial-mixed venous O2content difference(A-VΔO2), O2consumption(VO2), plasma epinephrine(E) and norepinephrine(NE), mean arterial pressure(MAP), and core (Tc) and ambient(Tamb) temperatures. A vascular resistance index(R) was calculated (MAP ÷ Q). Each animal was studied in a thermoneutral environment (CONTROL) and 30 min. after the nadir of ECS. Results (Mean±SEM):We conclude that ECS results in (1) ↑QSM(↑ heat production) due to ↓R (2) ↓QGI, QKI, and QAD due to ↑R (3)↑A-VΔO2with unchanged E and NE. We speculate that changes in R result initially from metabolic autoregulation(↓R) followed by altered peripheral sympathetic tone(↑R). |
| Databáze: |
Supplemental Index |
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