| Autor: |
Maertzdorf, Wiel J, Slaaf, Dick W, Tangelder, Geert J, Blanco, Carlos E |
| Zdroj: |
Pediatric Research; August 1988, Vol. 24 Issue: 2 p263-263, 1p |
| Abstrakt: |
In 37 newborn infants with polycythaemia (with or without clinical symptoms) we performed a PPET. CBFV was measured before, 3, 12 and 24 hours after PPET. In a matched control group (N=15) CBFV was measured 6, 12, and 24 hours after birth. CBFV was recorded with a bidirectional 5 mHz continuous wave velocimeter. Recordings were made from the anterior cerebral and left mid cerebral arteries. The study group included 14 term infants, 11 preterm infants and 12 small for date infants. The peripheral venous Hct decreased from 72.5±2.7% X + SD) to 60.1 ± 4.2% after PPET. Heart rate and blood pressure did not change significantly. Peak systolic flow velocity (PSFV), peak diastolic flow velocity (PDFV) and mean flow (AUTC) increased significantly (P < 0.001) at 3 hours after PPET. The PI (PSFV-PDFV/PSFV) did not change significantly (0.1 < P < 0.5). CBFV obtained after PPET did not differ from CBFV in the control group and this remained constant at 12 and 24 hours thereafter. When analysing the changes in CBFV after PPET we observed conparable changes of flow parameters in the 3 subgroups of infants within the study group. We concluded that lowering the Hct by PPET in polycythaemic newborn infants normalises the CBFV after 3 hours and this remains constant up to 24 hours. This could help to clarify indications to PPET in polycythemic newborns. |
| Databáze: |
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