| Autor: |
Uhrmann, Susan, Marks, Keith H, Maisels, M Jeffrey, Friedman, Zvi, Murray, Frederick, Kulin, Howard, Kaplan, Michael, Utiger, Robert |
| Zdroj: |
Pediatric Research; April 1977, Vol. 11 Issue: 4 p432-432, 1p |
| Abstrakt: |
Serum thyroxin values (T4) were found to be low in 6 of 1350 admissions when the tests were ordered on clinical grounds. Hypothyroidism was confirmed in 3 infants, but the remaining 3 had transient depressions of 3, due to binding globulin (TBG) deficiency. Consequently, a longitudinal study was carried out on 9 infants (gestation 30-34 wks). Data are means ± SE.Four infants displayed a transient decline in T4 levels (≥40% of their 24h value) at some time between 72 hrs and 2 wks, a pattern unlike the normal full-term baby. These data indicate that for infants admitted to a NICU: 1. The incidence of hypothyroidism may be higher than in the general population; 2. T4 values vary markedly and falsely low values may occur frequently; 3. A TSH determination on or after 72 hours of life may be the most appropriate screen for hypothyroidism; 4. Transient decrements in T4 may reflect a transient TBG deficiency. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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