| Autor: |
Mombaerts, Laurent, Mauroy, Alexandre, Gonçalves, Jorge |
| Zdroj: |
IFAC-PapersOnLine; January 2016, Vol. 49 Issue: 26 p109-113, 5p |
| Abstrakt: |
Circadian clocks consist of complex networks that coordinate the daily cycle of most organisms. In light/dark cycles, the clock is synchronized (or entrained) by the environment, which corresponds to a constant rephasing of the oscillations and leads to a steady state regime. Some circadian clocks are endogenous oscillators with rhythms of about 24-hours that persist in constant light or constant darkness. This operating mechanism with and without entrainment provides flexibility and robustness to the clock against perturbations. Most of the clock-oriented experiments are performed under constant photoperiodic regime, overlooking the transitory regime that takes place between light/dark cycles and constant light or darkness. This paper provides a comparative analysis of the informative potential of the transient time-series data with the other regimes for clock modelling. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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