| Autor: |
Lombardi, Christopher, Day, Jonathan, Chandrasoma, Nalin, Mitchell, David, Rodriguez, Michael J., Farmer, Jennifer L., Organ, Michael G. |
| Zdroj: |
Organometallics; 20240101, Issue: Preprints |
| Abstrakt: |
Herein we report the first example of (hetero)arylation of ammonia using a monoligated palladium-NHC complex. The new, rationally designed, precatalyst (DiMeIHeptCl)Pd(allyl)Cl featuring highly branched alkyl chains has been shown to be effective in selective aminations across a range of challenging substrates, including nitrogen-containing heterocycles and those featuring base-sensitive functionality. The less bulky Pd-PEPPSI-IPentClprecatalyst performs well for ortho-substituted aryl halides, giving monoarylated products in high yield with good selectivity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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