| Autor: |
Johnson, Deanna L, Hisel, Tina M, Phillips, Beth Bryles |
| Zdroj: |
The Annals of Pharmacotherapy; March 2003, Vol. 37 Issue: 3 p442-446, 5p |
| Abstrakt: |
OBJECTIVE: To evaluate the effect of cyclooxygenase-2 selective inhibitors (CSIs) on blood pressure.DATA SOURCES: Clinical literature accessed through MEDLINE (1966–May 2002). Key search terms included COX-2 selective inhibitors; anti-inflammatory agents, nonsteroidal; celecoxib; rofecoxib; and hypertension.DATA SYNTHESIS: Data from prospective studies on the effects of CSIs on blood pressure are conflicting. Several studies have reported increased blood pressure as an adverse effect of CSIs.CONCLUSIONS: Additional studies are needed to evaluate the effects of CSIs on blood pressure. CSIs should be used with caution in hypertensive patients and blood pressure monitored closely if a CSI is indicated. |
| Databáze: |
Supplemental Index |
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