Synthesis of Photoactive p-Azidotetrafluorophenylalanine Containing Peptide by Solid-Phase Fmoc Methodology

Autor: Redman, J. E., Ghadiri, M. R.
Zdroj: Organic Letters; December 2002, Vol. 4 Issue: 25 p4467-4469, 3p
Abstrakt: N-Fmoc-l-p-azidotetrafluorophenylalanine was prepared from achiral starting materials using an acetamidomalonate synthesis and enzymatic resolution. A photoactive peptide containing this fluorinated residue could be assembled using solid-phase Fmoc chemistry.
Databáze: Supplemental Index