| Autor: |
Tesfay, Lia, Schulz, Veronique V., Frank, Sander B., Lamb, Laura E., Miranti, Cindy K. |
| Zdroj: |
Molecular Biology of the Cell; August 2016, Vol. 27 Issue: 15 p2493-2504, 12p |
| Abstrakt: |
This study identifies a new mechanism by which the receptor tyrosine kinase Met promotes cell survival. The ectodomain and transmembrane domain of Met, independently of kinase activity, are required to maintain integrin α3β1 on the cell surface to prevent activation of intrinsic and extrinsic cell death pathways and maintain autophagic flux. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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