| Autor: |
Camici, Paolo, Chiriatti, Giampaolo, Lorenzoni, Roberto, Bellina, Riccardo C., Gistri, Roberto, Italiani, Gessica, Parodi, Oberdan, Salvadori, Piero A., Nista, Nicola, Papi, Lauro, L'abbate, Antonio |
| Zdroj: |
Journal of the American College of Cardiology; March 1991, Vol. 17 Issue: 4 p879-886, 8p |
| Abstrakt: |
To assess regional coronary reserve in hypertrophic cardiomyopathy, regional myocardial blood flow was measured in 23 patients with hypertrophic cardiomyopathy and 12 control subjects by means of nitrogen-13 ammonia and dynamic positron emission tomography. In patients with hypertrophic cardiomyopathy at baseline study, regional myocardial blood flow was 1.14 ± 0.43 ml/min per g in the hypertrophied (20 ± 3 mm) interventricular septum and 0.90 ± 0.35 ml/min per g (p < 0.05 versus septal flow) in the nonhypertrophied (10 ± 2 mm) left ventricular free wall. These were not statistically different from the corresponding values in control subjects (1.04 ± 0.25 and 0.91 ± 0.21 ml/min per g, respectively, p = NS). After pharmacologically induced coronary vasodilation (dipyridamole, 0.56 mg/kg intravenously over 4 min), regional myocardial blood flow in patients with hypertrophic cardiomyopathy increased significantly less than in control subjects both in the septum (1.63 ± 0.58 versus 2.99 ± 1.06 ml/min per g, p < 0.001) and in the free wall (1.47 ± 0.58 versus 2.44 ± 0.82 ml min per g, p < 0.001). |
| Databáze: |
Supplemental Index |
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