An association of human congenital cardiac malformations and drinking water contaminants

Autor: Goldberg, Stanley J., Lebowitz, Michael D., Graver, Ellen J., Hicks, Susan
Zdroj: Journal of the American College of Cardiology; July 1990, Vol. 16 Issue: 1 p155-164, 10p
Abstrakt: During an informal study in 1973 it was noted that approximately one third of patients with congenital heart disease lived in a small area in the Tucson Valley. In 1981 groundwater for a nearly identical area was found to be contaminated with trichloroethylene and to a lesser extent with dichioroethyiene and chromium. Contamination probably began during the 1950s. Affected wells were closed after discovery of contamination. This seqience of events allowed investigation of the prevalence of congenital heart disease in children whose parents were exposed to the contaminated water area as compared with children whose parents were never exposed to the contaminated water area. The contaminated water area contained 8.8% of the Tucson Valley population and 4.5% of the labor force.
Databáze: Supplemental Index