Effects of nicardipine, a calcium antagonist, on myocardial salvage and high energy phosphate stores in reperfused myocardial injury

Autor: Holt, William W., Wendland, Michael F., Derugin, Nikita, Wolfe, Christopher, Saeed, Maythem, Higgins, Charles B.
Zdroj: Journal of the American College of Cardiology; December 1990, Vol. 16 Issue: 7 p1736-1744, 9p
Abstrakt: The current study determined the effectiveness of nicardipine, a 1,4-dihydropyridine calcium antagonist, in preserving reperfused myocardium in a cat model of temporary coronary occlusion and ascertained if replenishment of myocardial phosphate stores during reperfusion as defined by phosphorus-31 nuclear magnetic resonance (NMR) spectroscopy was indicative of salvage.
Databáze: Supplemental Index