Quantitative exercise thallium-201 single photon emission computed tomography for the enhanced diagnosis of ischemic heart disease

Autor: Mahmarian, John J., Boyce, Terri M., Goldberg, Ronald K., Cocanougher, Mary K., Roberts, Robert, Verani, Mario S.
Zdroj: Journal of the American College of Cardiology; February 1990, Vol. 15 Issue: 2 p318-329, 12p
Abstrakt: The clinical utility of exercise thallium-201 single photon emission computed tomography was investigated in 360 consecutive patients who had concomitant coronary arteriography. Tomographic images were assessed visually and from computer-quantified polar maps. Sensitivity for detecting coronary artery disease was comparably high using quantitative and visual analysis, although specificity tended to improve using the former method (87% versus 76%, p = 0.09). Quantitative analysis was superior to the visual method for identifying left anterior descending (81% versus 68%, p < 0.05) and circumflex coronary artery (77% versus 60%, p < 0.05) stenoses and detected most patients (92%) with multivessel coronary artery disease. Multivessel involvement was correctly predicted in 65% of the patients with more than one critically stenosed vessel.
Databáze: Supplemental Index