| Autor: |
Neuhaus, Karl-Ludwig, Von Essen, Rainer, Tebbe, Ulrich, Vogt, Albrecht, Roth, Michael, Riess, Michael, Niederer, Walter, Forycki, Florian, Wirtzfeld, Alexander, Maeurer, Wolfgang, Limbourg, Peter, Merx, Wolfgang, Haerten, Klaus |
| Zdroj: |
Journal of the American College of Cardiology; April 1992, Vol. 19 Issue: 5 p885-891, 7p |
| Abstrakt: |
Thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) and anisoylated plasminogen streptokinase activator (APSAC) in myocardial infarction has been proved to reduce mortality. A new front-loaded infusion regimen of 100 mg of rt-PA with an initial bolus dose of 15 mg followed by an infusion of 50 mg over 30 min and 35 mg over 60 min has been reported to yield higher patency rates than those achieved with standard regimens of thrombolytic treatment. The effects of this front-loaded administration of rt-PA versus those obtained with APSAC on early patency and reocclusion of infarct-related coronary arteries were investigated in a randomized multicenter trial in 421 patients with acute myocardial infarction. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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