Transient myocardial dysfunction during pharmacologic vasodilation as an index of reduced coronary reserve: A coronary hemodynamic and echocardiographic study

Autor: Picano, Eugenio, Simonetti, Ignazio, Masini, Michele, Marzilli, Mario, Lattanzi, Fabio, Distante, Alessandro, De Nes, Maurizio, L’Abbate, Antonio
Zdroj: Journal of the American College of Cardiology; July 1986, Vol. 8 Issue: 1 p84-90, 7p
Abstrakt: Regional coronary flow reserve and regional myocardial contractility were evaluated in 29 patients after maximal pharmacologic coronary vasodilation (intravenous dipyridamole, 0.56 mg/kg body weight, administered over 4 minutes). Nineteen patients had a severe (80 to 99%) proximal and isolated stenosis of the left anterior descending coronary artery and 10 patients had normal coronary arteries; all had normal ventricular function under rest conditions. Myocardial contractility was assessed by means of continuous two-dimensional echocardiographic monitoring; coronary reserve was evaluated by coronary sinus thermodilution.
Databáze: Supplemental Index