| Autor: |
Kao, Andrew, Kriett, Jolene M., Gareth Tobler, H., Detloff, Barry L.S., Pritzker, Marc R., Woodrow Benson, D., Benditt, David G. |
| Zdroj: |
Journal of the American College of Cardiology; December 1984, Vol. 4 Issue: 6 p1188-1194, 7p |
| Abstrakt: |
Ventricular tachyarrhythmias associated with digitalis toxicity are believed to be due, in part, to cardiac glycoside-mediated increased central sympathetic neural activity. Because dopaminergic receptor agonists reduce sympathetic outflow, this study assessed effectiveness of the available dopaminergic agonist, bromocriptine, in slowing or terminating ouabain-induced ventricular tachycardia in anesthetized dogs. In all experiments, ouabain was administered intravenously (20 μg/kg body weight bolus injection, followed by 2.5 μg/kg per min infusion) until the onset of stable ventricular tachycardia. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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