Asymmetric septal hypertrophy in patients with aortic stenosis: An adaptive mechanism or a coexistence of hypertrophic cardiomyopathy

Autor: Hess, Otto M., Schneider, Jakob, Turina, Marco, Carroll, John D., Rothlin, Martin, Krayenbuehl, Hans P.
Zdroj: Journal of the American College of Cardiology; March 1983, Vol. 1 Issue: 3 p783-789, 7p
Abstrakt: Myocardial histologic features and left ventricular dynamics were assessed in 24 patients with severe aortic stenosis, 12 with (group 1) and 12 without (group 2) associated asymmetric septal hypertrophy. In 10 patients from group 1, echocardiography showed a septal/pos-terior wall ratio of 1.5; in the other 2, asymmetric septal hypertrophy was diagnosed by direct inspection at the time of surgery. Septal myectomy in all 12 patients in group 1 was completed at the time of aortic valve replacement. Septal histologic features were assessed from surgical specimens in 10 patients in group 1. Transseptal endomyocardial biopsy specimens of the anterolateral wall taken during preoperative cardiac catheterization were evaluated by light microscopy in 10 patients from group 1 and all patients of group 2.
Databáze: Supplemental Index