Comparison of baroreflex sensitivity and heart period variability after myocardial infarction

Autor: Bigger, J.Thomas, La Rovere, Maria Teresa, Steinman, Richard C., Fleiss, Joseph L., Rottman, Jeffrey N., Rolnitzky, Linda M., Schwartz, Peter J.
Zdroj: Journal of the American College of Cardiology; November 1989, Vol. 14 Issue: 6 p1511-1518, 8p
Abstrakt: In animals, baroreflex sensitivity is inversely related to the likelihood of ventricular fibrillation during myocardial ischemia. After myocardial infarction in human patients, reduced baroreflex sensitivity is associated with increased mortality. A reduced standard deviation of normal RR intervals over a 24 h period is also associated with reduced survival after myocardial infarction. Therefore, 32 normotensive men who had survived their first myocardial infarction were studied to define the relation between baroreflex sensitivity assessed with phenylephrine injection and three Hotter electrocardiographic measures of tonic vagal activity: the percent of successive normal RR intervals >50 ms, the root mean square successive difference of normal RR intervals and the power in the high frequency energy of the normal RR interval power spectrum.
Databáze: Supplemental Index