Tissue plasminogen activator: Toronto (TPAT) placebo-controlled randomized trial in acute myocardial infarction

Autor: Armstrong, Paul W., Baigrie, Ronald S., Daly, Paul A., Haq, Aminul, Gent, Michael, Roberts, Robin S., Freeman, Michael R., Burns, Robert, Liu, Peter, Morgan, Christopher D.
Zdroj: Journal of the American College of Cardiology; June 1989, Vol. 13 Issue: 7 p1469-1476, 8p
Abstrakt: The efficacy and safety of recombinant tissue plasminogen activator (rt-PA) administered on a dosing per weight basis was evaluated in a randomized, placebo-controlled, double-blind trial in 115 patients with acute myocardial infarction. The principal outcomes were global and regional left ventricular function in the distribution of the qualifying myocardial infarction, determined 9 days after the onset of symptoms.
Databáze: Supplemental Index