Left ventricular diastolic function: Comparison of pulsed doppler echocardiographic and hemodynamic indexes in subjects with and without coronary artery disease

Autor: Stoddard, Marcus F., Pearson, Anthony C., Kern, Morton J., Ratcliff, John, Mrosek, Denise G., Labovitz, Arthur J.
Zdroj: Journal of the American College of Cardiology; February 1989, Vol. 13 Issue: 2 p327-336, 10p
Abstrakt: To evaluate the influence of left ventricular chamber stiffness and relaxation on Doppler echocardiographic indexes of diastolic function, 35 patients (mean age 60 ± 12 years) were examined; 24 had coronary artery disease and 11 (Group I) had no cardiovascular disease. Micromanometer left ventricular pressure was recorded simultaneously with Doppler echocardiograms of mitral valve inflow and M-mode echocardiograms of left ventricular diameter. The chamber stiffness constant (k) was derived from the pressure-diameter relation. Relaxation was assessed by the isovolumic relaxation time constant (τ) derived from the exponential left ventricular pressure decay. The patients with coronary artery disease were classified into two groups on the basis of complete (Group II; n = 10) and incomplete (Group III; n = 14) relaxation.
Databáze: Supplemental Index