Effect of isolated proximal coronary stenotic lesions on distal myocardial perfusion during exercise

Autor: Nichols, Allen B., Buczek, Jo Ann, Schwann, Thomas A., Esser, Peter D., Blood, David K.
Zdroj: Journal of the American College of Cardiology; July 1988, Vol. 12 Issue: 1 p106-113, 8p
Abstrakt: This study tested the hypothesis that the absolute dimension of a coronary stenotic lesion is a more important determinant of its hemodynamic effect on regional myocardial perfusion during exercise than is relative percent stenosis. In 31 patients with an isolated lesion of the left anterior descending coronary artery, regional myocardial perfusion was determined from thallium-201 scans recorded in the left anterior oblique projection after symptom-limited treadmill exercise. Thallium-201 uptake in the distribution of the left anterior descending coronary artery was expressed as a ratio of thallium-201 uptake in the left circumflex artery distribution. Percent area stenosis, minimal cross-sectional area and mean diameter of each stenotic lesion were measured by computer-assisted cinevideodensitometric analysis of projected coronary arteriograms digitized in a 512 × 512 pixel matrix with 256 gray levels.
Databáze: Supplemental Index