| Autor: |
Rafferty, Mary Ellen, McCormick, Malkanthie I., Bopp, Lawrence H., Baltch, Aldona L., George, Mary, Smith, Raymond P., Rheal, Carol, Ritz, William, Schoonmaker, Diana |
| Zdroj: |
Infection Control & Hospital Epidemiology; May 1997, Vol. 18 Issue: 5 p342-344, 3p |
| Abstrakt: |
AbstractThe prevalence of, and clinical risk factors associated with, vancomycin-resistant enterococcal colonization were investigated in patients suspected of having Clostridium difficileinfection. Stools submitted for C difficilecytotoxin testing were screened for vancomycin-resistant enterococci (VRE). Isolates were speciated and characterized further by antibiotic susceptibility testing, DNA fingerprinting, and DNA:DNA hybridization for detection of specific vancomycin resistance genes. Of the 79 evaluable patients identified during a 3-month period, 16.5% were VRE-positive. The VRE isolates were genetically heterogeneous, although all carried the vanAgene. DNA fingerprinting data suggest that patient-to-patient transmission occurred, implicating colonized patients as potential reser voirs for VRE transmission. A positive C difficilecytotoxin assay and diabetes mellitus were the only identifiable risk factors associated with VRE colonization. Patients at risk for C difficileinfection therefore may serve as reser voirs for VRE. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
