| Autor: |
Gibson, F. S., Singh, A. K., Soumeillant, M. C., Manchand, P. S., Humora, M., Kronenthal, D. R. |
| Zdroj: |
Organic Process Research & Development; November 2002, Vol. 6 Issue: 6 p814-816, 3p |
| Abstrakt: |
A practical synthesis of l-valyl-pyrrolidine-(2R)-boronic acid (1) is detailed. A previously disclosed synthesis of 1 (Snow, R.; Kelly, T. R.; Adams, J.; Coutts, S.; Perry, C. (Boehringer Ingelheim Pharmaceuticals, Inc.). WO 93/10127, 1993) was significantly improved by developing an efficient process for recycling the costly chiral auxiliary (+)- pinanediol. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
