Effect of fat and carbohydrate composition on the gastric emptying of isocaloric feedings in premature infants

Autor: Siegel, Myron, Krantz, Bridget, Lebenthal, Emanuel
Zdroj: Gastroenterology; October 1985, Vol. 89 Issue: 4 p785-790, 6p
Abstrakt: The gastric empyting of six infant feedings (20 kcal/oz; whey to casein ratio, 60:40) with varying fat and carbohydrate composition was studied. Feedings contained either predominantly long-chain triglycerides (94%) or predominantly medium-chain triglycerides (94%) as the fat and lactose, glucose, or glucose polymers (Polycose) as the carbohydrate. Eleven premature infants were fed 22 ml/kg body wt of all six feedings over a 3–4-day period, and the volume of gastric contents was measured every 20 min using polyethylene glycol 4000 as the marker. Analysis of variance demonstrated that the use of medium-chain triglycerides resulted in faster gastric emptying than long-chain triglycerides (p < 0.001). Analysis of variance and Tukey's test showed that use of glucose polymers instead of glucose resulted in less volume of gastric contents at 40 min (p < 0.05). Use of glucose polymers instead of lactose resulted in less volume of gastric contents at 60 and 80 min (p < 0.05). Gastric empyting can be altered by changes in nutrient composition. The difference between medium-chain and long-chain triglycerides was more pronounced than the differences between the carbohydrates studied. Feedings with medium-chain triglycerides may be more suitable than long-chain triglycerides in patients with delayed gastric emptying.
Databáze: Supplemental Index