ChemInform Abstract: Inhibitors of Cyclic AMP Phosphodiesterase. Part 4. Synthesis and Evaluation of Potential Prodrugs of Lixazinone (N‐Cyclohexyl‐N‐methyl‐4‐((1,2,3,5‐tetrahydro‐2‐oxoimidazo(2,1‐b)quinazolin‐7‐yl)oxy)butyramide, RS‐82856).

Autor:	VENUTI, M. C., ALVAREZ, R., BRUNO, J. J., STROSBERG, A. M., GU, L., CHIANG, H.‐S., MASSEY, I. J., CHU, N., FRIED, J. H.
Zdroj:	ChemInform; May 1989, Vol. 20 Issue: 20 pno-no
Abstrakt:	Reductive amination of the nitrobenzaldehyde (I) with the glycine esters (IIa) or the amides (IIb) followed by reduction of the nitro group and cyclization with cyanogen bromide (III) gives the quinazolines (IV).
Databáze:	Supplemental Index
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