Light enhancement of in vitroantitumor activity of galactosylated phthalocyanines

Autor: Angelov, Ivan P., Kril, Anton I., Dimitrov, Rumen G., Borisova, Ekaterina G., Avramov, Lachezar A., Mantareva, Vanya N.
Zdroj: Photonics & Lasers in Medicine; May 2016, Vol. 5 Issue: 2 p123-140, 18p
Abstrakt: Background and objectives:Intensive research in the area of photodynamic therapy (PDT) has been made in recent years revealing it as a promising method for the treatment of tumors and inactivation of pathogenic microorganisms. However, for a broader application of this therapy one major challenge, namely a significant improvement of the targeted drug delivery and uptake, still remains. A possible solution of the selectivity problem could be the application of specifically functionalized photosensitizers, in particular phthalocyanine dyes.
Databáze: Supplemental Index