Correlation of Acute and Chronic Increases in Serum Gonadal Steroid Levels After Administration of Human Chorionic Gonadotropin**The opinions and assertions expressed herein are the private views of the authors and are not to be construed as official or as reflecting the view of the Department of the Army or the Department of Defense. Funding was provided by Clinical Investigation Service, Walter Reed Army Medical Center.

Autor:	Glass, Allan R., Vigersky, Robert A.
Zdroj:	Fertility and Sterility; July 1980, Vol. 34 Issue: 1 p41-45, 5p
Abstrakt:	The standard method for assessment of Leydig cell reserve requires determination of the increase in serum testosterone levels after several days of human chorionic gonadotropin (hCG) administration. To determine whether a shorter period of hCG administration would yield useful results, we measured the increases in serum testosterone and 17-hydroxyprogesterone levels 2 hours after an intramuscular injection of 4000 units of hCG (short hCG test) and compared these results with the increase in serum testosterone after 96 hours of hCG administration (standard hCG test). By 2 hours after the initial hCG injection, the control group showed significant percentage increases (mean±standard error) over basal levels for serum testosterone (24%±4%; P<0.001) and serum 17-hydroxyprogesterone (68%±11%; P<0.001). The percentage increase in serum testosterone during the standard hCG test correlated with both the acute percentage increase in serum testosterone (r=0.694, P<0.001) and the acute percentage increase in serum 17-hydroxyprogesterone (r=0.672, P<0.001).
Databáze:	Supplemental Index
Externí odkaz:	Zobrazit plný text záznamu