The Luteal Phase Defect: The Relative Frequency of, and Encouraging Response to, Treatment with Vaginal Progesterone**Presented in part at the Thirty-Sixth Annual Meeting of The American Fertility Society, March 18 to 22,1980, Houston, Tex.

Autor: Rosenberg, Sanford M., Luciano, Anthony A., Riddick, Daniel H.
Zdroj: Fertility and Sterility; July 1980, Vol. 34 Issue: 1 p17-20, 4p
Abstrakt: Three hundred and ninety-six patients were evaluated for primary and secondary infertility between December 1976 and May 1979 at a large referral center. Timed late luteal endometrial biopsies were routinely obtained as part of the work-up and were repeated for confirmation if subsequent menses did not occur within 2 days of the expected date. If both biopsies were abnormal, a diagnosis of luteal phase defect (LPD) was made and patients were treated with vaginal progesterone suppositories for a minimum of 6 months. LPD was discovered in 32 of 396 patients (8.1%); among those patients whose infertility was not complicated by other abnormalities, 9 of 13 conceived (70%) and 7 of 13 carried to term (54%). These data suggest an incidence higher than generally recognized and a very encouraging response to replacement therapy.
Databáze: Supplemental Index