| Autor: |
Spellacy, William N., Birk, Sharon A., Buhi, William C. |
| Zdroj: |
Fertility and Sterility; May 1980, Vol. 33 Issue: 5 p506-509, 4p |
| Abstrakt: |
The lymphocyte HLA types were determined for 13 women, who were then separated into a subgroup of those having a “high” risk for insulin-dependent diabetes mellitus (B8, B15, AW30) and a “low-risk” subgroup (B7, BW35). A 3-hour oral glucose tolerance test was conducted on each woman before starting on oral contraceptives (OC) and then 6 months after using them. Both blood glucose and plasma insulin levels were measured. The OC contained 0.035mg of ethinylestradiol and 0.4mg of norethindrone. There was a significantly higher 0.5-hour glucose value in the control test in the “high-risk” group. There was a significant elevation of the 1-hour plasma insulin value in the 6-month test for the “high-risk” group. The usefulness of the HLA prescreening of women prior to use of OC needs more study. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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