Autor: |
Lamberts, Steven W.J., Klijn, Jan G.M., de Lange, Sam A., Singh, Ram, Stefanko, Stanislaw Z., Birkenhäger, Jan C. |
Zdroj: |
Fertility and Sterility; June 1979, Vol. 31 Issue: 6 p614-619, 6p |
Abstrakt: |
The course of pregnancy achieved after bromocriptine therapy is described in nine patients with radiologically evident prolactin-secreting pituitary tumors. In six patients no complications occurred. No changes in sellar size or secondary endocrine deficiencies developed. In three patients, however, complications developed between the 22nd and 24th weeks of pregnancy. Despite prior external pituitary irradiation, one patient developed transient bitemporal hemianopsia and one patient had apoplexy of the pituitary tumor with transient paresis of the left abducens nerve. A third patient developed parasellar expansion of the pituitary tumor with bone destruction and paresis of the right abducens and oculomotor nerves. After transsphenoidal surgery the paresis of both nerves disappeared. Microscopically, the tissue removed at surgery was a chromophobe adenoma with focal fibrosis and calcifications without recent hemorrhages. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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