Autor: |
Peterson, William F., Prevost, Edward C., Edmunds, Frederick T., Hundley, J.Mason, Morris, Frank K. |
Zdroj: |
American Journal of Obstetrics and Gynecology; January 1956, Vol. 71 Issue: 1 p173-189, 17p |
Abstrakt: |
1.1. Fifteen cases of epidermoid carcinoma arising in benign cystic teratomas are reported, each accompanied by a short case history and photomicrograph.2.2. This complication, reported in about 1 per cent of all benign cystic teratomas, may be found to occur more frequently when these cysts are submitted to careful pathological examination.3.3. The average age at the time of diagnosis was 50.6 years, with 71 per cent of the cases diagnosed after the fortieth year.4.4. There are no symptoms that are indicative of malignant degeneration until extension has occurred.5.5. In these cases the malignancy arose in 8 cysts on the right side, in 6 cases on the left, and in one case the side is unknown. In 2 instances the malignancy arose in one of bilateral cysts.6.6. The pathology of the malignancy is briefly discussed and a photomicrograph of a representative area in each case is presented.7.7. Emphasis is placed on the necessity for careful pathological examination of each cyst. One must never allow the apparent benignity of a cystic teratoma to cause a false sense of security for the cyst cannot be labeled benign until it is submitted to careful microscopic examination.8.8. At the present time the treatment of choice is total removal of the uterus and adnexa in all but the very rare case.9.9. In 7 cases either extension of the malignancy or rupture of the cyst was noted. Each of these patients succumbed to the disease in a short length of time.10.10. Four patients have survived for 5 or more years—a salvage of 30.8 per cent. |
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