| Autor: |
Spellacy, William N., Teoh, Eng Soon, Buhi, William C., Birk, Sharon A., McCreary, Sally A. |
| Zdroj: |
American Journal of Obstetrics and Gynecology; February 1971, Vol. 109 Issue: 4 p588-598, 11p |
| Abstrakt: |
Studies of placental human chorionic somatomammotropin (HCS) in maternal serum were done to assess its usefulness as a placental function test. With the use of a solid-phase radioimmunoassay, HCS was measured in 1,378 serum samples from 506 pregnant women. The HCS values were similar in the normal, the blood factor Rh-sensitized, and the diabetes mellitus-complicated pregnancies. There was a decrease in the HCS values in proportion to the severity of maternal hypertension. An abnormally low fetal danger zone for HCS was determined, and the high-risk hypertensive pregnancies could be divided into those where serum HCS was above the zone (stillbirth rate zero) and those where the HCS values were in the zone (stillbirth rate 24.1). Significant correlations were found when comparisons were made between serum HCS and urinary estriol excretion or serum heat-stable alkaline phosphatase levels. It is hoped that the easy identification of a small group of hypertensive women whose fetuses are at great risk might lead to more intensive obstetric care of this group and an eventual lowering of the perinatal death rate. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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