| Autor: |
Armstrong, W.D., Wilt, J.G., Pritchard, E.T. |
| Zdroj: |
American Journal of Obstetrics and Gynecology; December 1968, Vol. 102 Issue: 7 p932-948, 17p |
| Abstrakt: |
In an attempt to determine the function of both the human amnion cell and its cytoplasmic lipid vacuole, term amnion membranes were biopsied and observed with the phase-contrast and electron microscopes. Biopsy studies indicate that although vacuolation is usually slightly greater in the reflected versus the placental amnion, the degree of vacuolation throughout a given membrane is quite similar and therefore consistent with generalized synchrony of amnion cell lipid production. Time-lapse studies of amnion cells in vitro support the belief that lipid vacuoles are not the result of degeneration, although cells which are vacuolated before culturing develop into monolayers relatively poorly. Ultrastructure studies indicate that human amnion cells contain structures necessary to support secretory activity and, further, the cytoplasmic lipid vacuole with its surrounding triple-layered membrane probably is a secretory product containing lipid. Based on these and other observations a proposed mechanism of amnion cell function is presented. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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